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Title | Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II |
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Journal, issue, pages | J. Med. Chem., Vol. 48, Page 5721-5727, Year 2005 |
Publish date | Apr 18, 2005 (structure data deposition date) |
![]() | Menchise, V. / De Simone, G. / Alterio, V. / Di Fiore, A. / Pedone, C. / Scozzafava, A. / Supuran, C.T. |
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Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | ![]() PDB-1ze8: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-HGB: ![]() ChemComp-PIU: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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