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-Structure paper
Title | ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity |
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Journal, issue, pages | J. Med. Chem., Vol. 48, Page 3953-3979, Year 2005 |
Publish date | Feb 23, 2005 (structure data deposition date) |
![]() | Mewshaw, R.E. / Edsall Jr., R.J. / Yang, C. / Manas, E.S. / Xu, Z.B. / Henderson, R.A. / Keith Jr., J.C. / Harris, H.A. |
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Methods | X-ray diffraction |
Resolution | 2.03 - 2.7 Å |
Structure data | ![]() PDB-1yy4: ![]() PDB-1yye: |
Chemicals | ![]() ChemComp-4NA: ![]() ChemComp-HOH: ![]() ChemComp-196: |
Source |
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![]() | TRANSCRIPTION / ESTROGEN RECEPTOR / ESTROGEN RECEPTOR BETA / ER-BETA / ER / ESTROGEN / NUCLEAR RECEPTOR / TRANSCRIPTION FACTOR / AGONIST |