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Structure paper

TitleCrystal structure of the Jak3 kinase domain in complex with a staurosporine analog
Journal, issue, pagesBlood, Vol. 106, Page 996-1002, Year 2005
Publish dateFeb 15, 2005 (structure data deposition date)
AuthorsBoggon, T.J. / Li, Y. / Manley, P.W. / Eck, M.J.
External linksBlood / PubMed:15831699
MethodsX-ray diffraction
Resolution2.55 Å
Structure data

PDB-1yvj:
Crystal structure of the Jak3 kinase domain in complex with a staurosporine analogue
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-DTV:
(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL

ChemComp-4ST:
1,2,3,4-TETRAHYDROGEN-STAUROSPORINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / TYROSINE KINASE; SCID; SEVERE COMBINED IMMUNODEFICIENCY; STAT5; STAT6; INTERLEUKIN-2; COMMON-GAMMA CHAIN

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