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-Structure paper
Title | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. |
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Journal, issue, pages | J. Biol. Chem., Vol. 280, Page 18202-18210, Year 2005 |
Publish date | Feb 14, 2005 (structure data deposition date) |
Authors | Biswal, B.K. / Cherney, M.M. / Wang, M. / Chan, L. / Yannopoulos, C.G. / Bilimoria, D. / Nicolas, O. / Bedard, J. / James, M.N.G. |
External links | J. Biol. Chem. / PubMed:15746101 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.5 Å |
Structure data | PDB-1yuy: PDB-1yv2: PDB-1yvx: PDB-1yvz: |
Chemicals | ChemComp-SO4: ChemComp-HOH: ChemComp-GOL: ChemComp-IPC: ChemComp-JPC: |
Source |
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Keywords | VIRAL PROTEIN / NS5B POLYMERASE GENOTYPE 2a / TRANSFERASE / NON-NUCLEOSIDE INHIBITOR |