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-Structure paper
Title | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. |
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Journal, issue, pages | J. Biol. Chem., Vol. 280, Page 18202-18210, Year 2005 |
Publish date | Feb 14, 2005 (structure data deposition date) |
![]() | Biswal, B.K. / Cherney, M.M. / Wang, M. / Chan, L. / Yannopoulos, C.G. / Bilimoria, D. / Nicolas, O. / Bedard, J. / James, M.N.G. |
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Methods | X-ray diffraction |
Resolution | 1.9 - 2.5 Å |
Structure data | ![]() PDB-1yuy: ![]() PDB-1yv2: ![]() PDB-1yvx: ![]() PDB-1yvz: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-GOL: ![]() ChemComp-IPC: ![]() ChemComp-JPC: |
Source |
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![]() | VIRAL PROTEIN / NS5B POLYMERASE GENOTYPE 2a / TRANSFERASE / NON-NUCLEOSIDE INHIBITOR |