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TitleStructural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Journal, issue, pagesEmbo J., Vol. 24, Page 674-682, Year 2005
Publish dateJan 24, 2005 (structure data deposition date)
AuthorsCampbell, E.A. / Pavlova, O. / Zenkin, N. / Leon, F. / Irschik, H. / Jansen, R. / Severinov, K. / Darst, S.A.
External linksEmbo J. / PubMed:15692574
MethodsX-ray diffraction
Resolution3.2 - 3.3 Å
Structure data

PDB-1ynj:
Taq RNA polymerase-Sorangicin complex
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-1ynn:
Taq RNA polymerase-rifampicin complex
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-SRN:
SORANGICIN A

ChemComp-ZN:
Unknown entry

ChemComp-RFP:
RIFAMPICIN / antibiotic*YM

Source
  • thermus aquaticus (bacteria)
KeywordsTRANSFERASE / RNA polymerase / RIFAMPICIN

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