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-Structure paper
Title | A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo. |
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Journal, issue, pages | J. Biol. Chem., Vol. 280, Page 9160-9169, Year 2005 |
Publish date | Jan 4, 2005 (structure data deposition date) |
![]() | Olivero, A.G. / Eigenbrot, C. / Goldsmith, R. / Robarge, K. / Artis, D.R. / Flygare, J. / Rawson, T. / Sutherlin, D.P. / Kadkhodayan, S. / Beresini, M. ...Olivero, A.G. / Eigenbrot, C. / Goldsmith, R. / Robarge, K. / Artis, D.R. / Flygare, J. / Rawson, T. / Sutherlin, D.P. / Kadkhodayan, S. / Beresini, M. / Elliott, L.O. / DeGuzman, G.G. / Banner, D.W. / Ultsch, M. / Marzec, U. / Hanson, S.R. / Refino, C. / Bunting, S. / Kirchhofer, D. |
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Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | ![]() PDB-1ygc: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-SO4: ![]() ChemComp-905: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / inverted oxy-anion hole |