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-Structure paper
Title | Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD(+) and NADP(+). |
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Journal, issue, pages | FEBS Lett., Vol. 579, Page 763-767, Year 2005 |
Publish date | Dec 28, 2004 (structure data deposition date) |
Authors | Leitgeb, S. / Petschacher, B. / Wilson, D.K. / Nidetzky, B. |
External links | FEBS Lett. / PubMed:15670843 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.4 Å |
Structure data | PDB-1ye4: PDB-1ye6: |
Chemicals | ChemComp-SO4: ChemComp-NAD: ChemComp-HOH: ChemComp-NAP: |
Source |
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Keywords | OXIDOREDUCTASE / beta-alpha-barrel AKR aldo-keto reductase coenzyme specificity NAD / beta-alpha-barrel AKR aldo-keto reductase coenzyme specificity NADP |