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-Structure paper
Title | Refined Solution Structure of the LpxC-TU-514 Complex and pK(a) Analysis of an Active Site Histidine: Insights into the Mechanism and Inhibitor Design |
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Journal, issue, pages | Biochemistry, Vol. 44, Page 1114-1126, Year 2005 |
Publish date | Nov 4, 2004 (structure data deposition date) |
Authors | Coggins, B.E. / McClerren, A.L. / Jiang, L. / Li, X. / Rudolph, J. / Hindsgaul, O. / Raetz, C.R.H. / Zhou, P. |
External links | Biochemistry / PubMed:15667205 |
Methods | NMR (solution) |
Structure data | PDB-1xxe: |
Chemicals | ChemComp-ZN: ChemComp-TUX: |
Source |
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Keywords | HYDROLASE / LpxC; TU-514; LPS; lipid A; lipopolysaccharide UDP-3-O-acyl-N-acetylglucosamine deacetylase; metalloamidase; zinc metalloamidase |