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-Structure paper
Title | An Old Target Revisited: Two New Privileged Skeletons and an Unexpected Binding Mode For HIV-Protease Inhibitors |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 44, Page 3140-3144, Year 2005 |
Publish date | Sep 30, 2004 (structure data deposition date) |
Authors | Specker, E. / Boettcher, J. / Lilie, H. / Heine, A. / Schoop, A. / Muller, G. / Griebenow, N. / Klebe, G. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:15822136 |
Methods | X-ray diffraction |
Resolution | 1.5 - 1.73 Å |
Structure data | PDB-1xl2: PDB-1xl5: |
Chemicals | ChemComp-CL: ChemComp-189: ChemComp-GOL: ChemComp-HOH: ChemComp-190: |
Source |
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Keywords | HYDROLASE / Aspartyl Protease; HIV Protease; Pyrrolidine Inhibitor / Aspartyl Protease / HIV Protease / Amidhydroxysulfone Inhibitor |