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TitleSubstrate Binding is Required for Assembly of the Active Conformation of the Catalytic Site in Ntn Amidotransferases: Evidence from the 1.8 Angstrom Crystal Structure of the Glutaminase Domain of Glucosamine 6-Phosphate Synthase
Journal, issue, pagesStructure, Vol. 4, Page 801-810, Year 1996
Publish dateSep 14, 2004 (structure data deposition date)
AuthorsIsupov, M.N. / Obmolova, G. / Butterworth, S. / Badet-Denisot, M.-A. / Badet, B. / Polikarpov, I. / Littlechild, J.A. / Teplyakov, A.
External linksStructure / PubMed:8805567
MethodsX-ray diffraction
Resolution1.8 - 1.85 Å
Structure data

PDB-1xff:
Glutaminase domain of glucosamine 6-phosphate synthase complexed with glutamate
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1xfg:
Glutaminase domain of glucosamine 6-phosphate synthase complexed with l-glu hydroxamate
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-GLU:
GLUTAMIC ACID

ChemComp-HOH:
WATER

ChemComp-HGA:
GLUTAMINE HYDROXAMATE

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / COMPLEX (TRANSFERASE-INHIBITOR); GLUTAMINE AMIDOTRANSFERASE / GLUTAMINE AMIDOTRANSFERASE; N-TERMINAL NUCLEOPHILE

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