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| Title | Structure of human factor VIIa/tissue factor in complex with a peptide-mimetic inhibitor: high selectivity against thrombin by introducing two charged groups in P2 and P4. |
|---|---|
| Journal, issue, pages | Acta Crystallogr. ,Sect. F, Vol. 61, Page 169-173, Year 2005 |
| Publish date | Nov 10, 2004 (structure data deposition date) |
Authors | Kadono, S. / Sakamoto, A. / Kikuchi, Y. / Oh-Eda, M. / Yabuta, N. / Koga, T. / Hattori, K. / Shiraishi, T. / Haramura, M. / Kodama, H. ...Kadono, S. / Sakamoto, A. / Kikuchi, Y. / Oh-Eda, M. / Yabuta, N. / Koga, T. / Hattori, K. / Shiraishi, T. / Haramura, M. / Kodama, H. / Ono, Y. / Esaki, T. / Sato, H. / Watanabe, Y. / Itoh, S. / Ohta, M. / Kozono, T. |
External links | Acta Crystallogr. ,Sect. F / PubMed:16510984 |
| Methods | X-ray diffraction |
| Resolution | 2.6 Å |
| Structure data | ![]() PDB-1wss: |
| Chemicals | ![]() ChemComp-BGC: ![]() ChemComp-FUC: ![]() ChemComp-CA: ![]() ChemComp-3CB: ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE/BLOOD CLOTTING / SERINE PROTEASE / HYDROLASE-BLOOD CLOTTING COMPLEX |
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homo sapiens (human)
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