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TitleSynthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14.
Journal, issue, pagesJ. Mol. Biol., Vol. 259, Page 120-134, Year 1996
Publish dateFeb 26, 1996 (structure data deposition date)
AuthorsOren, D.A. / Zhang, A. / Nesvadba, H. / Rosenwirth, B. / Arnold, E.
External linksJ. Mol. Biol. / PubMed:8648640
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1vrh:
HRV14/SDZ 880-061 COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SD8:
2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER

Source
  • human rhinovirus 14
KeywordsVIRUS / RHINOVIRUS COAT PROTEIN / ANTIVIRAL AGENTS / POLYPROTEIN / COAT PROTEIN / CORE PROTEIN / RNA POLYMERASE / HYDROLASE / THIOL PROTEASE / MYRISTYLATION / Icosahedral virus

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