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Structure paper

TitleFirst determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase.
Journal, issue, pagesJ. Biochem. (Tokyo), Vol. 135, Page 279-283, Year 2004
Publish dateNov 7, 2003 (structure data deposition date)
AuthorsInoue, T. / Okano, Y. / Kado, Y. / Aritake, K. / Irikura, D. / Uodome, N. / Okazaki, N. / Kinugasa, S. / Shishitani, H. / Matsumura, H. ...Inoue, T. / Okano, Y. / Kado, Y. / Aritake, K. / Irikura, D. / Uodome, N. / Okazaki, N. / Kinugasa, S. / Shishitani, H. / Matsumura, H. / Kai, Y. / Urade, Y.
External linksJ. Biochem. (Tokyo) / PubMed:15113825
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1v40:
First Inhibitor Complex Structure of Human Hematopoietic Prostaglandin D Synthase
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GSH:
GLUTATHIONE

ChemComp-O16:
3-(1,3-BENZOTHIAZOL-2-YL)-2-(1,4-DIOXO-1,2,3,4-TETRAHYDROPHTHALAZIN-6-YL)-5-[(E)-2-PHENYLVINYL]-3H-TETRAAZOL-2-IUM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE / PGDS / GST / SIGMA-2 CLASS GST / LIGASE

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