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TitleCross-Talk between Thiamin Diphosphate Binding and Phosphorylation Loop Conformation in Human Branched-Chain {Alpha}-Keto Acid Decarboxylase/Dehydrogenase
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 32968-, Year 2004
Publish dateApr 5, 2004 (structure data deposition date)
AuthorsLi, J. / Wynn, R.M. / Machius, M. / Chuang, J.L. / Karthikeyan, S. / Tomchick, D.R. / Chuang, D.T.
External linksJ. Biol. Chem. / PubMed:15166214
MethodsX-ray diffraction
Resolution1.8 - 2 Å
Structure data

PDB-1v11:
CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-1v16:
CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1v1m:
CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1v1r:
CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-TPP:
THIAMINE DIPHOSPHATE

ChemComp-BEN:
BENZAMIDINE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / KETOACID DEHYDROGENASE / BRANCHED-CHAIN / MULTI-ENZYME COMPLEX / ACYLATION / OXIDATIVE DECARBOXYLATION / MAPLE SYRUP URINE DISEASE / THIAMINE PHOSPHATE / PHOSPHORYLATION / OXIDATIVE DECARBOXYLATION MAPLE SYRUP URINE DISEASE / THIAMINE DIPHOSPHATE / FLAVOPROTEIN / THIAMIN DIPHOSPHATE

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