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TitleCrystal structure of the complex of UMP/CMP kinase from Dictyostelium discoideum and the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-uridyl) pentaphosphate (UP5A) and Mg2+ at 2.2 A: implications for water-mediated specificity.
Journal, issue, pagesBiochemistry, Vol. 35, Page 9716-9727, Year 1996
Publish dateJan 7, 1998 (structure data deposition date)
AuthorsScheffzek, K. / Kliche, W. / Wiesmuller, L. / Reinstein, J.
External linksBiochemistry / PubMed:8703943
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1uke:
UMP/CMP KINASE FROM SLIME MOLD
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-UP5:
P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE

ChemComp-HOH:
WATER

Source
  • dictyostelium discoideum (eukaryote)
KeywordsNUCLEOTIDE MONOPHOSPHATE KINASE / NMP KINASE / NUCLEOTIDE SPECIFICITY / PHOSPHORYL TRANSFER / BISUBSTRATE INHIBITOR

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