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Structure paper

TitleNew phenolic inhibitors of yeast homoserine dehydrogenase
Journal, issue, pagesBioorg. Med. Chem., Vol. 12, Page 3825-3830, Year 2004
Publish dateJun 29, 2004 (structure data deposition date)
AuthorsEjim, L. / Mirza, I.A. / Capone, C. / Nazi, I. / Jenkins, S. / Chee, G.L. / Berghuis, A.M. / Wright, G.D.
External linksBioorg. Med. Chem. / PubMed:15210149
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1tve:
Homoserine Dehydrogenase in complex with 4-(4-hydroxy-3-isopropylphenylthio)-2-isopropylphenol
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-178:
4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsOXIDOREDUCTASE / antifungal; small molecule screening; amino acid biosynthesis

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