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TitleStructure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 62, Page 312-323, Year 2006
Publish dateJun 27, 2004 (structure data deposition date)
AuthorsHurt, D.E. / Widom, J. / Clardy, J.
External linksActa Crystallogr. ,Sect. D / PubMed:16510978
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-1tv5:
Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-A26:
(2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide / medication*YM

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-ORO:
OROTIC ACID

ChemComp-N8E:
3,6,9,12,15-PENTAOXATRICOSAN-1-OL / C8E5, detergent*YM

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsOXIDOREDUCTASE / alpha-beta barrel; tim barrel

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