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Structure paper

TitleThe crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 53483-53490, Year 2004
Publish dateJun 22, 2004 (structure data deposition date)
AuthorsMorais-de-Sa, E. / Pereira, P.J.B. / Saraiva, M.J. / Damas, A.M.
External linksJ. Biol. Chem. / PubMed:15469931
MethodsX-ray diffraction
Resolution1.8 - 1.85 Å
Structure data

PDB-1tt6:
The orthorhombic crystal structure of transthyretin in complex with diethylstilbestrol
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1tz8:
The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-DES:
DIETHYLSTILBESTROL / medication, hormone*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-CO3:
CARBONATE ION

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Amyloid / Transthyretin / Diethylstilbestrol / Protein stabilization

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