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-Structure paper
Title | Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase. |
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Journal, issue, pages | Protein Eng., Vol. 9, Page 69-75, Year 1996 |
Publish date | Dec 5, 1995 (structure data deposition date) |
![]() | Finer-Moore, J.S. / Fauman, E.B. / Morse, R.J. / Santi, D.V. / Stroud, R.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.2 - 2.9 Å |
Structure data | ![]() PDB-1tsv: ![]() PDB-1tsw: ![]() PDB-1tsx: ![]() PDB-1tsy: ![]() PDB-1tsz: |
Chemicals | ![]() ChemComp-UMP: ![]() ChemComp-HOH: ![]() ChemComp-PO4: |
Source |
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![]() | TRANSFERASE / METHYLTRANSFERASE / NUCLEOTIDE BIOSYNTHESIS |