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Structure paper

TitleStructure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: binding at the active site despite an "open" flexible loop conformation.
Journal, issue, pagesProtein Sci., Vol. 1, Page 1578-1584, Year 1992
Publish dateNov 19, 1992 (structure data deposition date)
AuthorsVerlinde, C.L. / Witmans, C.J. / Pijning, T. / Kalk, K.H. / Hol, W.G. / Callens, M. / Opperdoes, F.R.
External linksPubMed:1304889
MethodsX-ray diffraction
Resolution2.84 Å
Structure data

PDB-1tsi:
STRUCTURE OF THE COMPLEX BETWEEN TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AND N-HYDROXY-4-PHOSPHONO-BUTANAMIDE: BINDING AT THE ACTIVE SITE DESPITE AN "OPEN" FLEXIBLE LOOP
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

Chemicals

ChemComp-4PB:
N-HYDROXY-4-PHOSPHONO-BUTANAMIDE

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei brucei (eukaryote)
KeywordsISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)

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