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TitleNon-steroidal anti-inflammatory drugs as potent inhibitors of phospholipase A2: structure of the complex of phospholipase A2 with niflumic acid at 2.5 Angstroms resolution.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 61, Page 1579-1586, Year 2005
Publish dateMay 21, 2004 (structure data deposition date)
AuthorsJabeen, T. / Singh, N. / Singh, R.K. / Sharma, S. / Somvanshi, R.K. / Dey, S. / Singh, T.P.
External linksActa Crystallogr. ,Sect. D / PubMed:16301791
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1td7:
Interactions of a specific non-steroidal anti-inflammatory drug (NSAID) with group I phospholipase A2 (PLA2): Crystal structure of the complex formed between PLA2 and niflumic acid at 2.5 A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NFL:
2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • naja sagittifera (cobra)
KeywordsHYDROLASE / Phospholipase A2 / Enzyme / Inhibitor

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