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Structure paper

TitleCrystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase.
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 19933-19938, Year 2003
Publish dateApr 7, 2004 (structure data deposition date)
AuthorsTabernero, L. / Rodwell, V.W. / Stauffacher, C.V.
External linksJ. Biol. Chem. / PubMed:12621048
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1t02:
Crystal structure of a Statin bound to class II HMG-CoA reductase
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-LVA:
(3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • pseudomonas mevalonii (bacteria)
KeywordsOXIDOREDUCTASE / Statin / HMG-CoA reductase / complex

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