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-Structure paper
Title | Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 14, Page 3063-3068, Year 2004 |
Publish date | Mar 18, 2004 (structure data deposition date) |
Authors | Wendt, M.D. / Geyer, A. / McClellan, W.J. / Rockway, T.W. / Weitzberg, M. / Zhao, X. / Mantei, R. / Stewart, K. / Nienaber, V. / Klinghofer, V. / Giranda, V.L. |
External links | PubMed:15149645 |
Methods | X-ray diffraction |
Resolution | 1.84 - 2 Å |
Structure data | PDB-1sqa: PDB-1sqo: PDB-1sqt: |
Chemicals | ChemComp-SO4: ChemComp-UI1: ChemComp-HOH: ChemComp-UI2: ChemComp-UI3: |
Source |
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Keywords | HYDROLASE / plasminogen activation / Serine protease / Glycoprotein / Kringle / EGF-like domain |