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-Structure paper
| Title | Discovery of an allosteric site in the caspases |
|---|---|
| Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 101, Page 12461-12466, Year 2004 |
| Publish date | Feb 25, 2004 (structure data deposition date) |
Authors | Hardy, J.A. / Lam, J. / Nguyen, J.T. / O'Brien, T. / Wells, J.A. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:15314233 |
| Methods | X-ray diffraction |
| Resolution | 2.8 - 3 Å |
| Structure data | ![]() PDB-1shj: ![]() PDB-1shl: |
| Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-NXN: ![]() ChemComp-FXN: |
| Source |
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Keywords | HYDROLASE / cysteine protease / allosteric / inhibitor / central cavity / caspase / protease / central-cavity / dimer interface |
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homo sapiens (human)
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