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| Title | Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors |
|---|---|
| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 14, Page 2233-2239, Year 2004 |
| Publish date | Dec 18, 2003 (structure data deposition date) |
Authors | Sutton, J.C. / Bolton, S.A. / Davis, M.E. / Hartl, K.S. / Jacobson, B. / Mathur, A. / Ogletree, M.L. / Slusarchyk, W.A. / Zahler, R. / Seiler, S.M. / Bisacchi, G.S. |
External links | Bioorg. Med. Chem. Lett. / PubMed:15081015 |
| Methods | X-ray diffraction |
| Resolution | 1.7 Å |
| Structure data | ![]() PDB-1rxp: |
| Chemicals | ![]() ChemComp-CA: ![]() ChemComp-SO4: ![]() ChemComp-169: ![]() ChemComp-HOH: |
| Source |
|
Keywords | HYDROLASE / TRYPTASE INHIBITOR; SERINE PROTEASE; AZETIDINONE |
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