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Structure paper

TitleCrystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands
Journal, issue, pagesBiochemistry, Vol. 43, Page 5170-, Year 2004
Publish dateDec 9, 2003 (structure data deposition date)
AuthorsMulichak, A.M. / Lu, W. / Losey, H.C. / Walsh, C.T. / Garavito, R.M.
External linksBiochemistry / PubMed:15122882
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1rrv:
X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-TYD:
THYMIDINE-5'-DIPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • amycolatopsis orientalis (bacteria)
KeywordsTRANSFERASE/ANTIBIOTIC / GT-B / GLYCOSYLTRANSFERASE / ROSSMANN FOLD / GLYCOPEPTIDE / VACOSAMYCIN / ANTIBIOTIC / TRANSFERASE-ANTIBIOTIC COMPLEX

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