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-Structure paper
Title | Crystal structures of a multidrug-resistant human immunodeficiency virus type 1 protease reveal an expanded active-site cavity. |
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Journal, issue, pages | J. Virol., Vol. 78, Page 3123-3132, Year 2004 |
Publish date | Dec 3, 2003 (structure data deposition date) |
Authors | Logsdon, B.C. / Vickrey, J.F. / Martin, P. / Proteasa, G. / Koepke, J.I. / Terlecky, S.R. / Wawrzak, Z. / Winters, M.A. / Merigan, T.C. / Kovari, L.C. |
External links | J. Virol. / PubMed:14990731 |
Methods | X-ray diffraction |
Resolution | 1.86 - 2.7 Å |
Structure data | PDB-1rpi: PDB-1rq9: PDB-1rv7: |
Chemicals | ChemComp-GLC: ChemComp-HOH: ChemComp-DMQ: ChemComp-AB1: |
Source |
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Keywords | HYDROLASE / HIV protease / AIDS / polyprotein / aspartyl portease / multi-drug resistance / aspartyl protease / Lopinavir |