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Structure paper

TitleCrystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.
Journal, issue, pagesJ. Mol. Biol., Vol. 337, Page 355-365, Year 2004
Publish dateDec 1, 2003 (structure data deposition date)
AuthorsXu, R.X. / Rocque, W.J. / Lambert, M.H. / Vanderwall, D.E. / Luther, M.A. / Nolte, R.T.
External linksJ. Mol. Biol. / PubMed:15003452
MethodsX-ray diffraction
Resolution2 - 2.13 Å
Structure data

PDB-1ro6:
Crystal structure of PDE4B2B complexed with Rolipram (R & S)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1ro9:
CRYSTAL STRUCTURES OF THE CATALYTIC DOMAIN OF PHOSPHODIESTERASE 4B2B COMPLEXED WITH 8-Br-AMP
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

PDB-1ror:
CRYSTAL STRUCTURES OF THE CATALYTIC DOMAIN OF PHOSPHODIESTERASE 4B2B COMPLEXED WITH AMP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-ARS:
ARSENIC

ChemComp-ROL:
ROLIPRAM / antidepressant, inhibitor*YM

ChemComp-HOH:
WATER

ChemComp-8BR:
8-BROMO-ADENOSINE-5'-MONOPHOSPHATE

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PDE / Rolipram / crystal / 8-Br-AMP / AMP

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