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Structure paper

TitleShort Lexitropsin that Recognizes the DNA Minor Groove at 5'-ACTAGT-3': Understanding the Role of Isopropyl-thiazole.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 126, Page 11338-11349, Year 2004
Publish dateNov 28, 2003 (structure data deposition date)
AuthorsAnthony, N.G. / Johnston, B.F. / Khalaf, A.I. / MacKay, S.P. / Parkinson, J.A. / Suckling, C.J. / Waigh, R.D.
External linksJ. Am. Chem. Soc. / PubMed:15355117
MethodsNMR (solution)
Structure data

PDB-1rmx:
A SHORT LEXITROPSIN THAT RECOGNIZES THE DNA MINOR GROOVE AT 5'-ACTAGT-3': UNDERSTANDING THE ROLE OF ISOPROPYL-THIAZOLE
Method: SOLUTION NMR

PDB-1rn9:
A SHORT LEXITROPSIN THAT RECOGNIZES THE DNA MINOR GROOVE AT 5'-ACTAGT-3': UNDERSTANDING THE ROLE OF ISOPROPYL-THIAZOLE
Method: SOLUTION NMR

Chemicals

ChemComp-AIK:
N-[3-(DIMETHYLAMINO)PROPYL]-2-({[4-({[4-(FORMYLAMINO)-1-METHYL-1H-PYRROL-2-YL]CARBONYL}AMINO)-1-METHYL-1H-PYRROL-2-YL]CARBONYL}AMINO)-5-ISOPROPYL-1,3-THIAZOLE-4-CARBOXAMIDE

KeywordsDNA / MINOR-GROOVE-DNA COMPLEX / SIDE-BY-SIDE BINDING / DNA RECOGNITION / DOUBLE HELIX

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