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-Structure paper
Title | Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor IBMX suggest a conformation determinant of inhibitor selectivity |
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Journal, issue, pages | J. Biol. Chem., Vol. 279, Page 13095-13101, Year 2004 |
Publish date | Nov 22, 2003 (structure data deposition date) |
![]() | Huai, Q. / Liu, Y. / Francis, S.H. / Corbin, J.D. / Ke, H. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.05 - 2.1 Å |
Structure data | ![]() PDB-1rkp: ![]() PDB-1zkn: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-MG: ![]() ChemComp-IBM: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / pde5A / viagra / IBMX / PROTEIN-INHIBITOR COMPLEX / INHIBITOR SELECTIVITY |