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TitleStructure of an allosteric inhibitor of LFA-1 bound to the I-domain studied by crystallography, NMR, and calorimetry
Journal, issue, pagesBiochemistry, Vol. 43, Page 2394-2404, Year 2004
Publish dateNov 5, 2003 (structure data deposition date)
AuthorsCrump, M.P. / Ceska, T.A. / Spyracopoulos, L. / Henry, A. / Archibald, S.C. / Alexander, R. / Taylor, R.J. / Findlow, S.C. / O'Connell, J. / Robinson, M.K. / Shock, A.
External linksBiochemistry / PubMed:14992576
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-1rd4:
An allosteric inhibitor of LFA-1 bound to its I-domain
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-L08:
1-ACETYL-4-(4-{4-[(2-ETHOXYPHENYL)THIO]-3-NITROPHENYL}PYRIDIN-2-YL)PIPERAZINE

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM

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