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-Structure paper
Title | Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. |
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Journal, issue, pages | Protein Eng. Des. Sel., Vol. 17, Page 625-633, Year 2004 |
Publish date | Oct 31, 2003 (structure data deposition date) |
Authors | Mahan, S.D. / Ireton, G.C. / Knoeber, C. / Stoddard, B.L. / Black, M.E. |
External links | Protein Eng. Des. Sel. / PubMed:15381761 |
Methods | X-ray diffraction |
Resolution | 1.12 - 1.58 Å |
Structure data | PDB-1r9x: PDB-1r9y: PDB-1r9z: PDB-1ra0: PDB-1ra5: PDB-1rak: |
Chemicals | ChemComp-FE: ChemComp-MG: ChemComp-GOL: ChemComp-HOH: ChemComp-FPY: |
Source |
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Keywords | HYDROLASE / cytosine deaminase / alpha-beta barrel / hexamer / domain swap / D314G mutant / amino hydrolase / D314A mutant / D314S mutant / CONFORMATIONAL CHANGE |