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TitleCrystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 100, Page 12654-12659, Year 2003
Publish dateSep 22, 2003 (structure data deposition date)
AuthorsSchiering, N. / Knapp, S. / Marconi, M. / Flocco, M.M. / Cui, J. / Perego, R. / Rusconi, L. / Cristiani, C.
External linksProc. Natl. Acad. Sci. USA / PubMed:14559966
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1r0p:
Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met in complex with the microbial alkaloid K-252a
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1r1w:
CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-KSA:
K-252A

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Receptor tyrosine kinase / Signal Transduction / Grb2 / Shc

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