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-Structure paper
Title | Crystal structures of staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. |
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Journal, issue, pages | J. Med. Chem., Vol. 47, Page 1325-1328, Year 2004 |
Publish date | Sep 9, 2003 (structure data deposition date) |
Authors | Douangamath, A. / Dale, G.E. / D'Arcy, A. / Almstetter, M. / Eckl, R. / Frutos-Hoener, A. / Henkel, B. / Illgen, K. / Nerdinger, S. / Schulz, H. ...Douangamath, A. / Dale, G.E. / D'Arcy, A. / Almstetter, M. / Eckl, R. / Frutos-Hoener, A. / Henkel, B. / Illgen, K. / Nerdinger, S. / Schulz, H. / MacSweeney, A. / Thormann, M. / Treml, A. / Pierau, S. / Wadman, S. / Oefner, C. |
External links | J. Med. Chem. / PubMed:14998322 |
Methods | X-ray diffraction |
Resolution | 1.04 - 1.68 Å |
Structure data | PDB-1qxw: PDB-1qxy: PDB-1qxz: |
Chemicals | ChemComp-CO: ChemComp-ACT: ChemComp-M1C: ChemComp-HOH: ChemComp-M2C: ChemComp-M3C: |
Source |
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Keywords | HYDROLASE / pita bread fold |