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TitlePhospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution.
Journal, issue, pagesBiochemistry, Vol. 43, Page 14577-14583, Year 2004
Publish dateAug 17, 2003 (structure data deposition date)
AuthorsSingh, N. / Jabeen, T. / Somvanshi, R.K. / Sharma, S. / Dey, S. / Singh, T.P.
External linksBiochemistry / PubMed:15544328
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-1q7a:
Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-OPB:
4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE / antiinflammatory*YM

ChemComp-MOH:
METHANOL

ChemComp-HOH:
WATER

Source
  • daboia russellii pulchella (snake)
KeywordsHYDROLASE / Phospholipase A2 / Venom / Antiinflammatory compound

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