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Structure paper

TitleStructural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418.
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 45937-45945, Year 2003
Publish dateAug 8, 2003 (structure data deposition date)
AuthorsBhat, R. / Xue, Y. / Berg, S. / Hellberg, S. / Ormo, M. / Nilsson, Y. / Radesater, A.C. / Jerning, E. / Markgren, P.O. / Borgegard, T. ...Bhat, R. / Xue, Y. / Berg, S. / Hellberg, S. / Ormo, M. / Nilsson, Y. / Radesater, A.C. / Jerning, E. / Markgren, P.O. / Borgegard, T. / Nylof, M. / Gimenez-Cassina, A. / Hernandez, F. / Lucas, J.J. / Diaz-Nido, J. / Avila, J.
External linksJ. Biol. Chem. / PubMed:12928438
MethodsX-ray diffraction
Resolution1.94 Å
Structure data

PDB-1q5k:
crystal structure of Glycogen synthase kinase 3 in complexed with inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

Chemicals

ChemComp-TMU:
N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)UREA

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase-inhibitor complex

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