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Title3,5,6-Trisubstituted Naphthostyrils as CDK2 Inhibitors
Journal, issue, pagesBIOORG. MED. CHEM., Vol. 13, Page 2465-2468, Year 2003
Publish dateApr 15, 2003 (structure data deposition date)
AuthorsLiu, J.-J. / Dermatakis, A. / Lukacs, C.M. / Konzelmann, F. / Chen, Y. / Kammlott, U. / Depinto, W. / Yang, H. / Yin, X. / Schutt, A. ...Liu, J.-J. / Dermatakis, A. / Lukacs, C.M. / Konzelmann, F. / Chen, Y. / Kammlott, U. / Depinto, W. / Yang, H. / Yin, X. / Schutt, A. / Simcox, M.E. / Luk, K.-C.
External linksBIOORG. MED. CHEM. / PubMed:12852944
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1p2a:
The structure of cyclin dependent kinase 2 (CKD2) with a trisubstituted naphthostyril inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-5BN:
5-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / cyclin dependent kinase / naphthostyril oxindole

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