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Structure paper

TitleTowards Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerophosphate Synthase: Crystal Structures of a Ternary Complex and the Free Enzyme
Journal, issue, pagesBiochemistry, Vol. 42, Page 7003-7012, Year 2003
Publish dateApr 1, 2003 (structure data deposition date)
AuthorsChaudhuri, B.N. / Lange, C. / Myers, R.S. / Davisson, V.J. / Smith, J.L.
External linksBiochemistry / PubMed:12795595
MethodsX-ray diffraction
Resolution2.4 - 2.5 Å
Structure data

PDB-1ox4:
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1ox5:
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1ox6:
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NI:
NICKEL (II) ION

ChemComp-POP:
PYROPHOSPHATE 2-

ChemComp-HOH:
WATER

ChemComp-1PR:
PHOSPHORIC ACID MONO-[5-({[5-CARBAMOYL-3-(5-PHOSPHONOOXY-5-DEOXY-RIBOFURANOSYL)- 3H-IMIDAZOL-4-YLAMINO]-METHYL}-AMINO)-2,3,4-TRIHYDROXY-PENTYL] ESTER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSFERASE / LYASE / COMPLEX CYCLIZATION; IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE

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