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-Structure paper
Title | Insights Into Cyclin Groove Recognition. Complex Crystal Structures and Inhibitor Design Through Ligand Exchange |
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Journal, issue, pages | Structure, Vol. 11, Page 1537-, Year 2003 |
Publish date | Jul 30, 2003 (structure data deposition date) |
![]() | Kontopidis, G. / Andrews, M. / Mcinnes, C. / Cowan, A. / Powers, H. / Innes, L. / Plater, A. / Griffiths, G. / Paterson, D. / Zheleva, D. ...Kontopidis, G. / Andrews, M. / Mcinnes, C. / Cowan, A. / Powers, H. / Innes, L. / Plater, A. / Griffiths, G. / Paterson, D. / Zheleva, D. / Lane, D. / Green, S. / Walkinshaw, M. / Fischer, P. |
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Methods | X-ray diffraction |
Resolution | 2.4 - 2.9 Å |
Structure data | ![]() PDB-1okv: ![]() PDB-1okw: ![]() PDB-1ol1: ![]() PDB-1ol2: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / KINASE-CYCLIN COMPLEX / CYCLIN A / INHIBITOR / LIGAND EXCHANGE / DRUG DESIGN / PEPTIDOMIMETICS / CELL CYCLE / KINASE / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX / COMPLEX(KINASE-CYCLIN) / SERINE/THREONINE-PROTEIN KINASE / ATP-BINDING / CELL DIVISION / MITOSIS / PHOSPHORYLATION |