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Structure paper

TitleInsights Into the Mode of Inhibition of Human Mitochondrial Monoamine Oxidase B from High-Resolution Crystal Structures
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 100, Page 9750-, Year 2003
Publish dateJul 8, 2003 (structure data deposition date)
AuthorsBinda, C. / Li, M. / Hubalek, F. / Restelli, N. / Edmondson, D.E. / Mattevi, A.
External linksProc. Natl. Acad. Sci. USA / PubMed:12913124
MethodsX-ray diffraction
Resolution1.7 - 3.1 Å
Structure data

PDB-1oj9:
HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH 1,4-DIPHENYL-2-BUTENE
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1oja:
HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH ISATIN
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1ojc:
HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH N-(2-aminoethyl)-p-chlorobenzamide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1ojd:
HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH Lauryldimethylamine-N-oxide (LDAO)
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-1PB:
1,4-DIPHENYL-2-BUTENE

ChemComp-HOH:
WATER

ChemComp-ISN:
ISATIN

ChemComp-LAZ:
N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE

ChemComp-LDA:
LAURYL DIMETHYLAMINE-N-OXIDE / LDAO, detergent*YM

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / FAD-CONTAINING AMINE OXIDASE / MAOB / FLAVOPROTEIN

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