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TitleStructural Analysis of the Native and Drug-Resistant HIV-1 Proteinases Complexed with an Aminodiol Inhibitor
Journal, issue, pagesProtein Pept. Lett., Vol. 3, Page 399-, Year 1996
Publish dateSep 16, 1996 (structure data deposition date)
AuthorsKervinen, J. / Thanki, N. / Zdanov, A. / Tino, J. / Barrish, J. / Lin, P.F. / Colonno, R. / Riccardi, K. / Samanta, H. / Wlodawer, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 - 2.1 Å
Structure data

PDB-1odw:
Native HIV-1 Proteinase
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1odx:
HIV-1 Proteinase mutant A71T, V82A
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-0E8:
di-tert-butyl {iminobis[(2S,3S)-3-hydroxy-1-phenylbutane-4,2-diyl]}biscarbamate

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsHydrolase/Hydrolase Inhibitor / PROTEINASE / RETROPEPSIN / RETROVIRUS / HIV / Hydrolase-Hydrolase Inhibitor complex / ASPARTYL PROTEASE

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