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TitleTryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 25919-, Year 2003
Publish dateOct 23, 2002 (structure data deposition date)
AuthorsAlphey, M.S. / Gabrielsen, M. / Micossi, E. / Leonard, G.A. / Mcsweeney, S.M. / Ravelli, R.B.G. / Tetaud, E. / Fairlamb, A.H. / Bond, C.S. / Hunter, W.N.
External linksJ. Biol. Chem. / PubMed:12707277
MethodsX-ray diffraction
Resolution1.3 - 2.35 Å
Structure data

PDB-1o73:
Tryparedoxin from Trypanosoma brucei
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

PDB-1o7u:
Radiation induced tryparedoxin-I
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1o85:
Radiation-reduced Tryparedoxin-I
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1o8w:
Radiation-reduced Tryparedoxin-I
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1o8x:
Mutant tryparedoxin-I Cys43Ala
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-1oc8:
TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY MR
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1oc9:
TRYPAREDOXIN II FROM C.FASCICULATA solved by MR
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • trypanosoma brucei brucei (eukaryote)
  • crithidia fasciculata (eukaryote)
KeywordsELECTRON TRANSPORT / TRYPAREDOXIN / TRYPANOSOMATID / TRYPANOSOMA BRUCEI / THIOREDOXIN / TRYPAREDOXIN-I / SYNCHROTRON RADIATION / DISULFIDE BONDS TRYPAREDOXIN / CRITHIDIA FASCICULATA / TRYPANOSOME / ANOMALOUS DISPERSION / OXIDATIVE STRESS / OXIDOREDUCTASE / TRYPAREDOXIN II

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