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Structure paper

TitleSubstrate-dependent competency of the catalytic triad of prolyl oligopeptidase.
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 44597-44605, Year 2002
Publish dateSep 15, 2002 (structure data deposition date)
AuthorsSzeltner, Z. / Rea, D. / Juhasz, T. / Renner, V. / Mucsi, Z. / Orosz, G. / Fulop, V. / Polgar, L.
External linksJ. Biol. Chem. / PubMed:12228249
MethodsX-ray diffraction
Resolution1.4 - 1.6 Å
Structure data

PDB-1o6f:
PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, D641A MUTANT WITH BOUND PEPTIDE LIGAND SUC-GLY-PRO
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1o6g:
PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, D641N MUTANT WITH BOUND PEPTIDE LIGAND SUC-GLY-PRO
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-GLY:
GLYCINE

ChemComp-PRO:
PROLINE

ChemComp-SIN:
SUCCINIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • sus scrofa (pig)
KeywordsHYDROLASE / PROLYL OLIGOPEPTIDASE / AMNESIA / ALPHA/ BETA-HYDROLASE / BETA-PROPELLER

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