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Title | Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain |
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Journal, issue, pages | Mol. Endocrinol., Vol. 17, Page 107-116, Year 2003 |
Publish date | Jan 20, 2003 (structure data deposition date) |
![]() | Huber, B.R. / Desclozeaux, M. / West, B.L. / Cunha-Lima, S.T. / Nguyen, H.T. / Baxter, J.D. / Ingraham, H.A. / Fletterick, R.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.9 Å |
Structure data | ![]() PDB-1nq0: ![]() PDB-1nq1: |
Chemicals | ![]() ChemComp-4HY: ![]() ChemComp-ARS: ![]() ChemComp-HOH: |
Source |
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![]() | HORMONE/GROWTH FACTOR RECEPTOR / thyroid hormone receptor / HORMONE-GROWTH FACTOR RECEPTOR COMPLEX / ALPHA HELICAL / LIGAND BINDING DOMAIN |