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Structure paper

TitleThe crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes
Journal, issue, pagesNucleic Acids Res., Vol. 31, Page 1464-1469, Year 2003
Publish dateNov 27, 2002 (structure data deposition date)
AuthorsTemperini, C. / Messori, L. / Orioli, P. / Di Bugno, C. / Animati, F. / Ughetto, G.
External linksNucleic Acids Res. / PubMed:12595554
MethodsX-ray diffraction
Resolution2.15 Å
Structure data

PDB-1nab:
The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-44D:
7-[5-(4-AMINO-5-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY)-4-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY]-6,9,11-TRIHYDROXY-9-(2-HYDROXY-ACETYL)-7,8,9,10-TETRAHYDRO-NAPHTHACENE-5,12-DIONE

ChemComp-HOH:
WATER

KeywordsDNA / right handed dna / double helix / complexed with drug

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