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Structure paper

TitleRNA Synthesis in a Cage-Structural Studies of Reovirus Polymerase lambda3
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 111, Page 733-745, Year 2002
Publish dateSep 24, 2002 (structure data deposition date)
AuthorsTao, Y. / Farsetta, D.L. / Nibert, M.L. / Harrison, S.C.
External linksCell(Cambridge,Mass. ) / PubMed:12464184
MethodsX-ray diffraction
Resolution2.5 - 2.8 Å
Structure data

PDB-1muk:
reovirus lambda3 native structure
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1mwh:
REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1n1h:
Initiation complex of polymerase lambda3 from reovirus
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1n35:
lambda3 elongation complex with four phosphodiester bond formed
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1n38:
reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

ChemComp-GTG:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

ChemComp-G7M:
N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-CH1:
3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE

ChemComp-GH3:
3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE

ChemComp-U3H:
3'-DEOXY-URIDINE 5'-TRIPHOSPHATE

Source
  • reovirus sp.
  • mammalian orthoreovirus 3
KeywordsVIRAL PROTEIN / single subunit polymerase fold / fingers / palm / thumb / right hand configuration / polymerase / polymerase-cap analog complex / TRANSFERASE/RNA / initiation complex / TRANSFERASE-RNA COMPLEX / RNA polymerase / bracelet

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