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TitleHigh-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
Journal, issue, pagesJ. Mol. Biol., Vol. 332, Page 423-435, Year 2003
Publish dateAug 19, 2002 (structure data deposition date)
AuthorsRuzheinikov, S.N. / Muranova, T.A. / Sedelnikova, S.E. / Partridge, L.J. / Blackburn, G.M. / Murray, I.A. / Kakinuma, H. / Takashi, N. / Shimazaki, K. / Sun, J. ...Ruzheinikov, S.N. / Muranova, T.A. / Sedelnikova, S.E. / Partridge, L.J. / Blackburn, G.M. / Murray, I.A. / Kakinuma, H. / Takashi, N. / Shimazaki, K. / Sun, J. / Nishi, Y. / Rice, D.W.
External linksJ. Mol. Biol. / PubMed:12948492
MethodsX-ray diffraction
Resolution1.22 - 2.25 Å
Structure data

PDB-1mh5:
The Structure Of The Complex Of The Fab Fragment Of The Esterolytic Antibody MS6-164 and A Transition-State Analog
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1mie:
Crystal Structure Of The Fab Fragment of Esterolytic Antibody MS5-393
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-1mj7:
Crystal Structure Of The Complex Of The Fab fragment of Esterolytic Antibody MS5-393 and A Transition-State Analog
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-1mj8:
High Resolution Crystal Structure Of The Fab Fragment of The Esterolytic Antibody MS6-126
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-1mjj:
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12 AND A TRANSITION-STATE ANALOG
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1mju:
1.22 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12
Method: X-RAY DIFFRACTION / Resolution: 1.22 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HAL:
N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / CATALYTIC ANTIBODY / ESTER HYDROLYSIS / ESTEROLYTIC / FAB / IMMUNOGLOBULIN / TSA

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