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TitleHeavy Going: the Atomic Resolution Structure of a Topoisomerase II Poison Intercalating into DNA in Multiple Orientations Also Reveals a Multiple Adenine-Thymine Hydrogen Bonding Pattern
Journal, issue, pagesTo be Published
Publish dateJul 15, 2002 (structure data deposition date)
AuthorsTeixeira, S.C.M. / Thorpe, J.H. / Todd, A.K. / Cardin, C.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.1 Å
Structure data

PDB-1m69:
Atomic Resolution Structure of 5Br-9amino-DACA with d[CGTACG]2
Method: X-RAY DIFFRACTION / Resolution: 1.1 Å

Chemicals

ChemComp-DAX:
5-BROMO-N[2-(DIMETHYLAMINO)ETHYL]-9-AMINOACRIDINE-4-CARBOXAMIDE

ChemComp-SPM:
SPERMINE

ChemComp-HOH:
WATER

KeywordsDNA / atomic resolution / adenine-thymine disorder / topoisomerase II poison

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