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TitleCrystal Structure of Memapsin 2 (beta-Secretase) in Complex with Inhibitor OM00-3
Journal, issue, pagesBiochemistry, Vol. 41, Page 10963-10967, Year 2002
Publish dateJul 2, 2002 (structure data deposition date)
AuthorsHong, L. / Turner, R.T. / Koelsch, G. / Shin, D. / Ghosh, A.K. / Tang, J.
External linksBiochemistry / PubMed:12206667
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1m4h:
Crystal Structure of Beta-secretase complexed with Inhibitor OM00-3
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / MEMAPSIN2 / BASE / ASP2 / ALZHEIMER'S DISEASE / ASPARTIC PROTEASE / ACID PROTEASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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